Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysis
نویسندگان
چکیده
منابع مشابه
Dynamic contact network between ribosomal subunits enables rapid large-scale rotation during spontaneous translocation
During ribosomal translation, the two ribosomal subunits remain associated through intersubunit bridges, despite rapid large-scale intersubunit rotation. The absence of large barriers hindering rotation is a prerequisite for rapid rotation. Here, we investigate how such a flat free-energy landscape is achieved, in particular considering the large shifts the bridges undergo at the periphery. The...
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Microarrays have the capacity to measure the expression levels of thousands of genes simultaneously1. Although microarrays have revolutionized mRNA analysis, they are only a proxy for the actual amount of protein synthesis occurring in cells. Multiple levels of transcriptional and post-transcriptional regulation contribute to the inherent challenges of proteomic analysis. A direct method for an...
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ژورنال
عنوان ژورنال: BMC Systems Biology
سال: 2010
ISSN: 1752-0509
DOI: 10.1186/1752-0509-4-64